Histomorphological Effect of Dumpsite Waste Forage (calopogonium Mucunoides) on the Testes and Ovaries of Rabbit (oryctolagus Cuniculus)

Histomorphological effect of the feeding of dumpsite forage (Calapo -Calopogonium mucunoides) on the reproductive profile of rabbits (Oryctolagus cuniculus) was investigated. 30 rabbits; 20 females and 10 males were obtained and distributed randomly into two treatment groups of 10 females and 5 males. The forage, specifically Calapo (Calopogonium mucunoides) was fed to the two groups’ ad-libitum with the non-dumpsite fed group serving as the control. After a period of 20 weeks, the rabbits were sacrificed, organs (ovaries and testes) were removed and fixed immediately in Bouin’s fluid transported to the Laboratory for Histopathological analysis. Fixed tissues were cut at 2-3mm in thickness, processed to paraffin wax, cut at 5 microns, stained using Heamtoxylin and Eosin technique and observed histopathologically under light digital microscope. The results showed cellular hypertrophy in ovary of the dumpsite compared to the non dumped site which showed normal cellular pattern of the ovaries. For the testes, it showed moderate cellular abnormality, with area of hypertrophy from the dumped site compare to non dumped site showing normal cellular pattern of spermatogenic lining cell, leydig cell and good structural networking within normal constituency. In conclusion, feeding of dumpsite forages to rabbits could lead to germinal cell abnormalities and cytoarchitectural alterations and deleterious effect on reproductive morphology of rabbits